Parasite dose and the course of infection: a meta-analysis
Abstract: Although parasitic infections are enormously diverse, they share certain fundamental characteristics. One such characteristic is variation in exposure dose: hosts encounter different concentrations of parasites depending on where they are, how they behave, and who they interact with. This affects the probability that an infection will be established, but also influences the density of parasites within the host (parasite load) after establishment. The effects of exposure dose on parasite load are generally studied on a case-by-case basis, making it difficult to identify general patterns and predict the influence of dose on infection severity and transmission. I will present early results from a meta-analysis project that attempts to resolve this gap, by looking for general patterns in experimental infections published across the life sciences.
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