- They are endemic to China, and occur in mountain streams.
- They are expertly camouflaged against the rocky stream bottoms.
- Previously, it was considered a single species, but recently discovered to be at least five cryptic genetic lineages (perhaps species).
- It is possible that the southern species Andrias sligoi is the largest living amphibian.
- They are the largest of the few living species of ancient salamanders (family Cryptobranchidae).
- Large individuals can reach a body mass of 50 kg.
- Females lay eggs in underwater caves guarded and cared for by males for many weeks.
- Major threats to them include overexploitation, habitat degradation, and unintended admixture by cross breeding between cryptic lineages.
- They are farmed for meat in China, which is considered as a threat to wild populations.
- The Chinese giant salamander has been introduced to Japan and is a threat to the native Japanese giant salamander.
- It is assessed as Critically Endangered on the IUCN Red List.
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